Q: Is Coglavax® safe to use on animals younger than 2 weeks?
A: It is of no value to inject animals before 2 weeks of age but Coglavax® is quite safe to use in 2 week old animals if the circumstances require such an early vaccination. It is usually sufficient to give the first Coglavax® vaccination at about 6 to 12 weeks of age (or at weaning if no problems occur in young animals) and then a booster 4 weeks later.
Q: When using Coglavax® , why don’t I see any swelling on the animals? Does it mean the vaccine is not working?
A: The swelling at the injection site of vaccines is dependent on the adjuvant used and also the other ingredients of the vaccine eg. oil vaccines give a large swelling and alum vaccines no or very small swellings. Coglavax® contains an adjuvant that is used in childrens’ vaccines and so normally gives no swelling at the injection sites. Swellings that do occur are usually due to dirty needles used during the vaccination process.
Q: Can I use Coglavax® and Cevac® Chlamydia at the same time?
A: Yes this can be done because one is a dead vaccine and the other a live vaccine. Two live vaccines should not be used at the same time (unless it is stated on both their labels that it is safe to do so). Make sure that pregnant animals are not injected with the Cevac® Chlamydia as it is a live vaccine and could cause abortions.
FOR ANIMAL USE ONLY
COGLAVAX®
Reg. No. G3684 Act 36/1947, V06/24.4/180
INDICATIONS:
A polyvalent inactivated vaccine for the prevention of Clostridial infections in cattle and sheep.
STORAGE:
Store between 2 - 8 °C.
Protect from light.
Do not freeze.
COMPOSITION:
This vaccine contains antigens in sufficient quantities to obtain the following levels of antibodies in the serum of control animals:
Cl. perfringens type A, C and D: |
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Alpha toxoid | 2 IU/mℓ |
Beta toxoid | 10 IU/mℓ |
Epsilon toxoid | 5 IU/mℓ |
Cl. septicum toxoid | 2,5 IU/mℓ |
Cl. novyi type B toxoid | 3,5 IU/mℓ |
Cl. tetani toxoid | 2,5 IU/mℓ |
Cl. Chauvoei | 100 % protection |
Adjuvant aluminium hydroxide as Al(OH)3 q.s. | 0,6 - 0,8 % |
Preservative formaldehyde q.s. | < 0,05 % |
WARNINGS:
Vaccinate healthy animals only.
The vaccine contains an adjuvant which may result in a mild, temporary local reaction at the site of injection.
A small number of individuals may fail to develop an immune response in any group of animals as a result of immuno-incompetence or for other reasons.
As with most inactivated vaccines, significant development of immunity cannot be expected until two weeks after the second dose of the vaccination course. During the vaccination process, stressing of the animals should be avoided, particularly during the later stages of pregnancy when there is an increased risk of induction of abortion and metabolic disease conditions.
Occasional hypersensitivity reactions may occur.
Keep out of reach of children, uninformed persons and animals.
Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.
PRECAUTIONS:
Observe the usual aseptic precautions in the administration of this vaccine.
Do not mix with any other vaccine.
In case of accidental self-injection to the user, immediately consult a doctor.
Destroy any partially used packs by for example burning; dispose of all the vaccine containers when the vaccination is completed.
It is good vaccination practice not to allow vaccine to come into contact with human eyes or mucous membranes.
Wash and disinfect hands with a disinfectant after vaccination.
DIRECTIONS FOR USE: Use only as directed.
Shake well before use.
After first opening of the container, it is recommended to use the vaccine within 8 hours.
Administration is by subcutaneous injection in the loose skin on the upper side of the neck.
No alcohol or any other disinfectants should be used for sterilisation of the needles and syringes.
DOSAGE:
DOSAGE | FIRST VACCINATION | BOOSTER |
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| Dose/time of the 1st injection | Dose/time of the 2nd injection | |
SHEEP: |
Non pregnant ewes, rams | 2 mℓ at any time | 2 mℓ, 4 weeks after the 1st injection. | 2 mℓ, 1 year after the last injection or 4 - 6 weeks prior to challenge period. |
Pregnant ewes | 2 mℓ 6 - 9 weeks before the expected lambing date. | 2 mℓ, 4 weeks after the 1st injection and not later than 2 - 5 weeks before the expected lambing date. | 2 mℓ, 1 year after the last injection or not later than 2 - 5 weeks before the expected lambing date. |
Lambs | 2 mℓ at 2 weeks of age (unvaccinated). If the ewe was previously vaccinated, start the vaccination at 8 weeks of age. | 2 mℓ, 4 weeks after the 1st injection. | 2 mℓ, 1 year after the last injection or 4 - 6 weeks prior to challenge period. |
CATTLE: |
Calves weighing less than 100 kg | 2 mℓ at any time. | 2 mℓ, 6 weeks after the 1st injection. | 4 mℓ, 1 year after the last injection or not later than 2 - 4 weeks before the risk period. |
Calves and Adult cattle | 4 mℓ at any time. | 4 mℓ, 6 weeks after the 1st injection. | 4 mℓ, 1 year after the last injection or 4 - 6 weeks prior to challenge period. |
EFFICACY:
Cattle and Sheep:
For the active immunisation of cattle and sheep against infections caused by Cl. perfringens A, C and D, Cl. novyi B, Cl. septicum, Cl. tetani and Cl. chauvoei in the following bacterial disease conditions:
Pulpy Kidney Disease in sheep
Black Quarter in cattle and sheep
Gas Gangrene in cattle and sheep
Tetanus in cattle and sheep
Malignant Oedema in cattle and sheep
Enterotoxaemia (bloodgut) in adult sheep and lambs
IDENTIFICATION:
Clear brown vaccine suspension.
PRESENTATION:
100 mℓ, 500 mℓ, in plastic containers
REGISTRATION HOLDER:
CEVA Animal Health (Pty) Ltd
Reg. No. 1973/016009/07
P O Box 7707
Halfway House 1685
011 312 4088